SoulCalibur 6, Fire Emblem Switch, and DMC5 are all announced in the same year, in a timeline that I exist in.
So, things I've noticed upon careful review of the trailer:
-The art style and urban setting, along with the demons in the beginning fighting police forces looking remarkably like Stygian, has convinced me that either Capcom has incorporated a more urban art style and punk rock aesthetic to create a compromise between fans of DmC and DMC, or took the sequel ideas from DmC2 and incorporated in this game (because this does sound like the post-apocalyptic demon invasion setting that was teased at the end of DmC and and alluded to by a developer Q & A on this forum). I personally really like this, but I hope we see some of the more Gothic environments characteristic to the series...or even some of the Renaissance aesthetic that was in DMC4.
-The anatomy of the characters and grittier look reminds me of the change in art style that Resident Evil underwent for RE7, which I'm certainly in favor for.
-Nero is definitely the main character here (MASSIVE thumbs up from me), and his mannerisms and attire are STRIKINGLY similar to DmC Dante, a far cry from the more rage-filled and hot-blooded Nero we saw in DMC4
-It appears that Devil Bringer has been stolen from him and being used by some hooded figure (which everyone speculates is Vergil, but I have no idea how true that is)
-Nero's grapping mechanics are looking far more like Dante's Angel/Demon grab than the Devil Bringer abilities from DmC
-There's a part of a trailer where Nero activiates something on his arm and freezes a demon in place, with a set of cosmic gears like a clock holding the demon in place, impying a Time Stop mechanic like Witch Time from Bayonetta
-He's running his own demon-hunting business, as the Deadly Fortune novel said he would
-The bespectacled girl (whose teeth and cheeks look VERY strangely rendered on her CG model) appears to be someone who builds Nero's weapons, including his arm, since she states in the trailer: "That's why I built him that well-functioning arm...to kick demon ass!" and "My brilliant, badass work is worth every dime, and you know it!"
-There's a slow-mo shot in the trailer where the Girl catches a flying cigarette in her mouth, which reminds me of Dante catching and putting on his clothes during the opening of DmC
-She isn't the love interest from what I can tell, because when that hooded figure with Devil Bringer turns up in the trailer, Nero shouts: "Kyrie! Get back inside!" (Meaning my girl Kyrie is in the game, and they're still together <3)
-There's a shot in the trailer where Nero is clutching his severed, bleeding arm, with the Hooded Stranger departing victorious with Devil Bringer in hand. This could just be a flashback of the opening of the game...so the premise of the story, for Nero at least, seems to be to get Devil Bringer back. This could also explain the substitute mechanical arm that the Bespectacled Girl has built for him
-The setting is strange---there's some glimpses of city streets and metropolitan advertisement builboards a la Time Square, but there's also stretches of courtyards and chapels seen during the day. This may take place in Fortuna and a handful of other locales, or it's possible that this is all a more modernized version of Fortuna that's shed some of its medieval-centric architecture now that The Order of the Sword isn't in charge
-The music for this game sounds nothing like any of the tracks or themes heard in previous games, having a more techno/electronica tone to it. I did notice the lyric: "Bang, bang, bang, let me be your Devil Trigger", which definitely made me smile. There was some screamo rock playing on stage at the Microsoft Booth when Itsuno walked out, a song I didn't recognize...it may be in the game, so hardcore DMC music enthusiasts shouldn't fret. I just hope they don't go into dubstep overload like they did on several instances in DmC
-Dante riding the Motorcycle reminds me a lot of DMC2, which may clue us in where this game takes place, but that could be a stretch on my part
-Itsuno described this game as "the best game he's ever made, because he made it for [fans]"