I have never understood why people cheered so much for that line.
It's quite simple. Cause Nero, unlike DmC Dante, earned it through context. In 5, it was a legit expression of pent up anger and frustration towards a parent that never gave a damn about him. In DmC (and the DMC anime too if I remember correctly), that's where it hits the juvenile note cause the context in there is nothing of the sort. Context makes all the difference. Nero isn't new to swearing, he did it in DMC4 as well, and there too the context allowed the cursing to make some justified sense (in that case, he was venting against the man who kidnapped and used his beloved girl).
The **** you contest with the Succubus in the reboot was clearly done for the sake of trying to make Dante sound like a badass, but the context is devoid of any semblance of emotional subtext whatsoever cause the Succubus is a nobody to Dante, just a lowly boss that has no relevance to Dante at a personal level, unlike Sanctus in 4 and Vergil in 5.
The **** you line would get the same juvenile connotation for Nero if it were to become his catchphrase as the guy above proposed, stripped from a sensible context. There's nothing wrong with using swearing with a character to make it more "rough", however the difference between it ending up sounding like a childish idiot and actually legit all lies in the context in which the swearing is used. Context can either justify the cussing, or it can warrant an eye roll. Nero hasn't exactly been the most loved DMC character so for him, it could have gone the latter way fairly easily. Yet the cursing generally didn't bother anyone and worked for him in 4 and 5 for this very reason.