Huh... Yeah, like Zoey said the healing factor is a problem, without cyborgs near Raiden wouldn't be able to heal himself, but since Nero is part-demon he would have the healing advantage. Plus, he has Yamato, and Yamato can literally cut everything, no matter how fast Raiden is he can even catch him with the Devil Bringer and impale him. If Nero decides not to use Yamato, it would be another story. Red Queen is powerful, yes, but Raiden is a trained soldier since he was a kid, this depends more on the wielder than anything.