Here's the thing the guy in the red and blue tight's ,even though i am an avid fan, difficulties and background cannot be compared to Dante's. Am i saying one is more tragic than the other? no. BUT the background is extremely different. The spider dude is raised by his aunt and uncle after his parents die and faces difficulties in high school and later is bitten by a radioactive/genetically engineered/what-ever-else-you-wanna-call-it spider. And later swears to protect the people of his city after the death of his uncle that he blames himself for.
Now Dante, on the other hand, probably didn't know his mother and father. It's been confirmed he has been tortured, in orphanages and other institutes when he was growing up, by demons that only he (and a select few) can see. He also has to fend for himself since it seems that he doesn't know he has a brother and is labelled by the media and most people around him as a terrorist.
Now you might be asking yourself, "Why the balls is this douche telling me the history of these two?" well it's elementary my dear......Railazel....(sounded way better in my head). These two have different backgrounds and thus different views, tolerances, and attitudes. The red and blue tights dude...oh Spiderman there you go...is a normal guy whose life is transformed by being bitten by a spider. The incurring loss of his uncle and his following guilt is what drives him to be a hero and you know be responsible while at the same time allowing him to be this witty guy because the mask acts as another ego and really lets him loose. Dante is treated,presumably, badly (in light terms) at an early age and is treated like an outcast. He knows little about his parents and knows that he doesn't belong in this world, that he's the only one and that facilitates loneliness. Now these two factors contribute to his crude, lewd, and aggressive manner because he knows the demons are what caused all this to happen to him. Thus, confirming why Dante cursing is not a big deal.