Resident Evil 5 simply can’t be remade, at least not to the standards of Capcom’s best work. And so the answer is not to remake, but to rewrite.
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I disagree as I never found RE5 to be controversial. It's just average in that 80s/90s anime way. Japanese anime and games don't tend to portray non-japan well.
Since 5 and 6 are controversial in the fandom for being action focused, remaking them to be more horror focused would be a good idea.
I feel 6's strengths are in the new faces than Leon or Chris. So I'd highlight them more and switch the villians to President Svetlana from RE Dammation.
So setting RE9 outside of the states and having the main heroes and villians be local to the new setting would be a good way to go.