I'm not sure what I'd like. From what I've gathered, Devil May Cry 2 was made before it was decided to be a series, so... Indeed. Perhaps it isn't canon, or maybe he was just very serious on that little adventure. There were rare moments in the games that he was serious. Well, this really isn't the point. What I'm trying to get at is that I wouldn't really like a Devil May Cry 5 in that atmosphere. I also wasn't really a fan of Nero. It seemed like the fourth installment was trying to break the series away from Dante, to me, and I didn't like that at all. Still... Maybe in a fifth they could somehow say that Nero is possessed by Vergil, or some such thing. If they had all three of them together, I think it would get a little hectic. Three people who just so happen to have white hair and who just so happen to be demon-related and happen to be incredible swordsmen just doesn't make much sense to me.
I'm starting to get into the idea of going into Sparda's story a little. He's only referenced throughout the series, the actual deep history hasn't been given yet. Maybe that should be a Devil May Cry 6.
Maybe this game should be incredibly long. Something with three or four disks worth of play. The first disk should be Sparda's story. The second should be Dante's latest shenanigans, and the third should be about what's been happening with Vergil this whole time... God, he was a great character.