Naughty Dog's hotly anticipaited new title Uncharted 3 has broken records for the franchise, selling more than 1.1 million copies in its first week on sale, 30% higher than Uncharted 2's debut. This is the 4th biggest exclusive launch for a Playstation 3 game behind Gran Turismo 5, Metal Gear Solid 4 and God of War 3, further cementing its place as one of Sony's key exclusives. It's also the 12th biggest launch overall for the PS3.
Looking forward it's hard to estimate lifetime sales without knowledge on when/if it will be bundled, however 4-5 million is most likely.
Source: http://www.vgchartz.com/article/88411/uncharted-3-sells-more-than-1m-copies-in-first-week/
Impressive sales. It is an impressive game, that I must add.