Like I said, too gay. Cool enemies though.
Fine then. It's DmC, 3, 1, 4, 2. Either way, the reboot takes place before Dante earns his white-haired badassery we're all familiar with, as that's when he first starts calling himself Dante again (as evidenced by the trailer). IF they're following canon, then Vergil might be in the game as well; probably as a protagonist-turned-antagonist again, if we're lucky. Trish won't be in the game. Lady won't be either, unless they feature the events that sparked her quest for vengeance in the first place.