It's EXTREMELY rare, but some humans in real life have different color eyes. Although I know what you mean. I think the twin's eyes look demonic. They don't look human to me.
Anyways, I would say Arkham and Lady have heterochromia. What is that? I have no idea, but I know it's the reason why their eyes are like that. http://en.wikipedia.org/wiki/Heterochromia
People with heterochromia also might have eye colors thats unique and not usually a natural shade or color of the human eye. Like this one...http://www.flickr.com/photos/lindes/119738076/ Alot of animals have it too. (cats and dogs)
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