I know the room you mean DT, it's the one with the lazors where you get the Key of Chronus. The closest spawn to that in the Torture Chamber is Gladius and Scarecrows.
Hold can be a useful technique in that room just grab a Gladius and use it as a shield, it can be a it risky though cause if you do end up getting hit you will lose your shield. I would try and stay away from Buster grabs unless you DT a Gladius it won't really do too much damage and in that room the recovery time will punish you. Your best friend in this situation will be the invincibility from Neros DT, the hit does a fair bit of damage and it shouldn't be too hard to regain DT quickly from the flying squids. Charge Shot 3s and Exceed attacks also work really well against them.