judging off of the effort put into this reboot, and Antoniades comments in response to the fans (aggressive at times) I think there will definitely be a sequel. Without reading any spoilers (i refuse to haha) the fact that they re-imagined the story to be more cohesive, while retaining the core premise of devil may cry, I think now a sequel would be the next logical step. They have built a cohesive frame for a new canon, rather than the originals where the manga and animated series came after because the fans liked the series and the games lacked sufficient storytelling. With this, now they can rebuild the mythos, as it were, but they can do it "in-game", and revise additional content such as comics, anime, etc, built off of what they have spent this time establishing. Will it be the same as the originals? no, I think not. However, I am excited to see what direction they take